Famed monster slayer Gabriel Van Helsing is dispatched to Transylvania to assist the last of the Valerious bloodline in defeating Count Dracula. Anna Valerious reveals that Dracula has formed an unholy alliance with Dr. Frankenstein's monster and is hell-bent on exacting a centuries-old curse on her family.
For years, Blade has fought against the vampires in the cover of the night. But now, after falling into the crosshairs of the FBI, he is forced out into the daylight, where he is driven to join forces with a clan of human vampire hunters he never knew existed—The Nightstalkers. Together with Abigail and Hannibal, two deftly trained Nightstalkers, Blade follows a trail of blood to the ancient creature that is also hunting him—the original vampire, Dracula.
In the millenium version of this classic Gothic horror we find Abraham Van Helsing, who has tangled with Count Dracula in the past, working as an English antiques dealer. Simon is a vampire hunter in training under his apprenticeship.
Vlad Tepes is a great hero, but when he learns the Sultan is preparing for battle and needs to form an army of 1,000 boys, he vows to find a way to protect his family. Vlad turns to dark forces in order to get the power to destroy his enemies and agrees to go from hero to monster as he's turned into the mythological vampire, Dracula.
The church enlists a team of vampire-hunters to hunt down and destroy a group of vampires searching for an ancient relic that will allow them to exist in sunlight.
Vampire housemates try to cope with the complexities of modern life and show a newly turned hipster some of the perks of being undead.
Bella once again finds herself surrounded by danger as Seattle is ravaged by a string of mysterious killings and a malicious vampire continues her quest for revenge. In the midst of it all, she is forced to choose between her love for Edward and her friendship with Jacob, knowing that her decision has the potential to ignite the ageless struggle between vampire and werewolf. With her graduation quickly approaching, Bella is confronted with the most important decision of her life.
When Blade's mother was bitten by a vampire during pregnancy, she did not know that she gave her son a special gift while dying—all the good vampire attributes in combination with the best human skills. Blade and his mentor battle an evil vampire rebel who plans to take over the outdated vampire council, capture Blade and resurrect a voracious blood god.